Service

Mobile Genetic Element Analysis: Transposons, Integrons and IS

Mapping of transposons, integrons and insertion sequences.

Mobile genetic elements (MGEs) are DNA segments that move within and between genomes. Insertion sequences, transposons and integrons are the main ways resistance genes are collected and spread.

Mapping these elements shows which genes in your strain are mobile, and therefore which traits could be gained, lost or passed on.

What you receive

  • Insertion sequences, transposons and integrons with their positions
  • Integron gene cassettes, where present
  • Genomic islands and prophage-like regions
  • Resistance and virulence genes located next to mobile elements

How we do it

  1. 1

    Element detection

    The annotated genome is screened against databases of known mobile elements.

  2. 2

    Context mapping

    Genes around each element are listed, including resistance and virulence genes.

  3. 3

    Interpretation

    We highlight elements that affect safety or transfer risk.

When you need it

  • Explaining how a strain acquired its resistance genes
  • Assessing the stability of traits in production strains
  • Comparing mobile element content across isolates

Questions

Why do mobile elements matter for probiotics?

A resistance gene next to a transposon or on a plasmid may transfer to other bacteria, which is a key safety concern. See probiotic safety assessment.

Further reading

For Research Use Only. BacSeq Analytics provides bioinformatics analysis and interpretation services for microbial genomic research. The reports are intended for research and investigational purposes only and are not intended for clinical diagnosis.

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